MedDx BRCA Gene Test

• Require 5mL blood sample
• Test for breast cancer gene, Test for ovarian cancer gene
• Test brac1/2 genes
• Result in approximately 2-4 weeks
• Test conducted and analyzed by Macrogen Inc.　(Macrogen, Inc. was established in 1997 and is a listed company in South Korea. The Macrogen laboratory has both FDA (CLIA) and (CAP) certifications)

Meddx BRCA Gene Test

According to the statistics from Hong Kong Cancer Registry under Hospital Authority (HA) in 2021, there were over 35000 new cancer cases in Hong Kong in 2019, meaning that 96 people were diagnosed of cancer per day.

Breast cancer is one of the top killers of women in Hong Kong. It accounted for 13.7% of female cancer deaths in 2019. In 2018, there were more than 4,600 new cases. Ovarian cancer ranked third among female cancers. Brca stands for breast cancer gene and ovarian cancer gene. Brca gene testing is performed to predict the risk of breast cancer and ovarian cancer. Mutations in the Brca gene increase the risk of breast cancer or ovarian cancer.

Cancer is not an incurable disease. Early cancer genetic testing can help to confirm the diagnosis, make treatment decisions, and reduce the risk of cancer death.

BRCA Gene Test Result:

Before you decide to proceed with genetic testing, we want you to have an understanding of the possible test result you may receive. You are advice to discuss with your doctors before you decided to proceed the genetic tests …

If you test positive…

Means a pathogenic variant was identified in one of the genes on your test panel that increases your risk of developing cancer.

1. Genetic testing may help to guide your treatment options, including surgical decision making and considerations for different types of chemotherapy.
2. Importantly, genetic testing can also clarify your future cancer risk, allowing your physicians to assist you with prevention or early detection of cancer.
3. Since DNA is passed down from generation to generation, a positive genetic test result may provide helpful information about your family members’ own cancer risks.
4. It is important to know that not everyone with pathogenic variant will develop cancer, and the pathogenic variant only increases the likelihood of cancer.

If you test negative …

It means that the laboratory did not find a pathogenic variant in any of the genes that were analyzed. It is possible for a patient to have a variant in a gene, or portion of a gene, that is not included in this testing. It is also possible that a patient’s personal or family history of cancer may be due to factors that aren’t inherited.

Which Specialist will explain the report?

Maternal-fetal medicine (MFM) is a discipline of science that integrates traditional obstetrics and gynecology, radiology, genetics, reducing birth defects, and cultivating new birth talents. Maternal-fetal medicine covers the knowledge of gynecology, basic knowledge of pregnancy medicine, maternity health care, infants, obstetrics, molecular genetics, cytogenetics, and other aspects of knowledge and the advances in technology.

Maternal and fetal medicine specialists are qualified Hong Kong obstetrics and gynecology specialists, who are required to undergo 6 years of specialist training, receive more than 3 years of formal education with MFM certification, and have clinical practice experience. It is necessary to have the diagnosis and treatment ability of high-risk pregnancy, weekly medicine, emergency prenatal diagnosis, and obstetrics.

Source: Hong Kong Cancer Registry, Hospital Authority - 2019 Top Ten Cancers